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Motherboards

MSI X399 SLI Plus DDR4 AMD Motherboard

MPN MSI-X399-SLI-PLUS  ·  Brand MSI

The MSI X399 SLI Plus is an ATX motherboard for AMD Ryzen Threadripper (SocketTR4) processors, featuring 8-slot quad-channel DDR4 up to 128 GB, three M.2 slots, 4-Way SLI/CrossFire support, and Mystic Light RGB

Warranty 3 Years Chipset AMD® X399 Chipset Mounting 9 mounting holes
25,835.00

Inclusive of GST · GST invoice available

Out of stock
Warranty
3 Years
Dispatch
24–48 hrs
Returns
7-day
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Overview

The MSI X399 SLI Plus is a full-ATX motherboard built around the AMD X399 chipset, designed specifically for 1st and 2nd Generation AMD Ryzen Threadripper processors using the SocketTR4 interface. It is aimed at content creators, power users, and enthusiasts who demand a high-end desktop (HEDT) platform with maximum expandability and multi-GPU capability. On the memory front, the board provides eight DDR4 DIMM slots arranged in a quad-channel architecture, supporting capacities up to 128 GB. Supported speeds range from DDR4-2133 MHz at standard JEDEC profiles up to DDR4-3600 MHz via overclocking, with ECC UDIMM memory also supported for added data integrity in workstation deployments. Storage options are equally generous: three Key-M M.2 slots (each capable of PCIe 3.0 x4 or SATA 6 Gb/s), supplemented by eight SATA 6 Gb/s ports, with RAID 0, RAID 1, and RAID 10 configurations available for SATA devices. The M2_2 slot uniquely accommodates the longer 22110 (110 mm) M.2 form factor in addition to the standard 2242/2260/2280 sizes. Expansion slots comprise two PCIe 3.0 x16 slots, two PCIe 3.0 x8 slots, and two PCIe 2.0 x1 slots, enabling up to 4-Way NVIDIA SLI or 4-Way AMD CrossFire multi-GPU configurations. Additional power delivery to the PCIe x16 slots is provided via an onboard 6-pin ATX 12 V connector. Connectivity is handled by a single Intel I211 Gigabit LAN controller. The USB ecosystem includes, on the rear panel, two USB 3.1 Gen2 (10 Gbps) ports — one Type-A and one Type-C via the ASMedia ASM3142 controller — and eight USB 3.1 Gen1 Type-A ports sourced from the AMD CPU. Internal headers add further USB 3.1 Gen2 Type-C, Gen1, and USB 2.0 expansion. Audio is handled by a Realtek ALC1220 codec delivering 7.1-channel HD audio with S/PDIF optical output. MSI's Audio Boost 4 implementation uses dedicated audio PCB layering and premium components to reduce noise. RGB personalisation is supported via two onboard RGB LED headers and MSI's Mystic Light software, offering 16.8 million colours across 17 effects. Thermal management headers include one CPU fan, one water-pump, and four system fan connectors. Onboard debug tools include EZ Debug LED indicators, a Flash BIOS button, an OC button, and a clear-CMOS header. Verified Specifications: - Form Factor: ATX — 12 in. x 9.6 in. (30.4 cm x 24.3 cm), 9 mounting holes - Processor Support: 1st & 2nd Gen AMD Ryzen Threadripper, SocketTR4 - Chipset: AMD X399 - Memory: 8 x DDR4 DIMM, quad-channel, up to 128 GB; DDR4-2133 to 3600 (OC); ECC UDIMM supported - PCIe Slots: 2x PCIe 3.0 x16 | 2x PCIe 3.0 x8 | 2x PCIe 2.0 x1 - Multi-GPU: 4-Way NVIDIA SLI / 4-Way AMD CrossFire - Storage: 8x SATA 6 Gb/s | 3x M.2 (PCIe 3.0 x4 / SATA) - RAID: 0, 1, 10 (SATA, via X399 chipset) - Audio: Realtek ALC1220, 7.1-channel HD, S/PDIF optical out - LAN: Intel I211 Gigabit (x1) - USB Rear: 2x USB 3.1 Gen2 (Type-A + Type-C) | 8x USB 3.1 Gen1 Type-A | 2x USB 2.0 Type-A - RGB: 2x RGB LED headers, Mystic Light compatible - OS: Windows 10 64-bit - Warranty: 3 Years

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Datasheet

Warranty

3 Years

Chipset

AMD® X399 Chipset

Lan

1 x Intel® I211 Gigabit LAN controllers

USB

ASMedia® ASM3142 Chipset1 x USB 3.1 Gen2 (SuperSpeed USB 10Gbps) Type-C port on the back panel1 x USB 3.1 Gen2 (SuperSpeed USB 10Gbps) Type-A port on the back panelAMD® X399 Chipset1 x USB 3.1 Gen2 (SuperSpeed USB 10Gbps) Type-C port through the internal USB connector4 x USB 3.1 Gen1 (SuperSpeed USB) ports available through the internal USB connectors6 x USB 2.0 (High-speed USB) ports (2 Type-A ports on the back panel, 4 ports available through the internal USB connectors)AMD® CPU8 x USB 3.1 Gen1 (SuperSpeed USB) Type-A ports on the back panel

Raid

AMD® X399 ChipsetSupports RAID 0, RAID 1 and RAID 10 for SATA storage devices

Audio

Realtek® ALC1220 Codec7.1-Channel High Definition AudioSupports S/PDIF output

Slots

2x PCIe 3.0 x16 slots (PCIE_1, PCIE_4)2x PCIe 3.0 x8 slots (PCIE_3, PCIE_6)2x PCIE 2.0 x1 Slots

Memory

8 x DDR4 memory slots, support up to 128GBQuad channel memory architecture1Supports DDR4 3600 (OC)/ 3466(OC)/ 3333(OC)/ 3200(OC)/ 3066(OC)/ 2933(OC)/ 2800(OC)/ 2667(nonOC-by SPD)/2667(OC)/ 2400/ 2133 MHz2Supports ECC UDIMM memoryPlease refer the DIMM Slots section for more details.For the latest information about memory, please visit Msi Website

Storage

AMD® X399 Chipset8 x SATA 6Gb/s portsAMD® RYZEN THREADRIPPER Series Processors3 x M.2 ports (Key M)Supports up to PCIe 3.0 x4 and SATA 6Gb/sM2_1, M2_3 slots support 2242/ 2260 /2280 storage devicesM2_2 slot supports 2242/ 2260 /2280/ 22110 storage devices

Mounting

9 mounting holes

Multi-Gpu

Supports 4-Way NVIDIA® SLI™ TechnologySupports 4-Way AMD® CrossFire™ Technology

Processor

Supports 1st and 2nd Gen AMD® RYZEN™ THREADRIPPER™ Series Processors for SocketTR4

Dimensions

12 in. x 9.6 in. (30.4 cm x 24.3 cm)ATX Form Factor

Back Panel Ports

Clear CMOSPS/2 Combo PortUSB 3.1 Gen 1LAN PortHD Audio ConnectorsFlash BIOS ButtonUSB 2.0 PortLIGHTNING USB 3.1 Gen2 Type A COptical S/PDIF-Out

Operating System

Support for Windows® 10 64-bit

Internal Connectors

1 x 24-pin ATX main power connector2 x 8-pin ATX 12V power connector1 x 6-pin ATX 12V power connector18 x SATA 6Gb/s connectors2 x USB 2.0 connectors (supports additional 4 USB 2.0 ports)2 x USB 3.1 Gen1 connectors (supports additional 4 USB 3.1 Gen1 ports)1 x USB 3.1 Gen2 Type-C port1 x 4-pin CPU fan connector1 x 4-pin Water Pump connector4 x 4-pin system fan connectors2 x Front panel connectors1 x Front panel audio connector2 x RGB LED connector1 x TPM module connector1 x LED demo connector1 x Rest Button1 x Power Button1 x OC Button1 x Chassis Intrusion connector1 x clear CMOS headerProvides additional power to PCIe x16 slots

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