ASUS WS X299 Pro DDR4 Intel Motherboard
MPN ASUS-WS-X299-PRO · Brand ASUS · ATX
The ASUS WS X299 Pro DDR4 is an ATX workstation motherboard for Intel LGA2066 Core X-Series CPUs, supporting up to 128GB DDR4-4133, dual M.2 PCIe 3.0 x4 with heatsink, U.2, dual Gigabit LAN, and 3-Way SLI/CrossFireX multi-GPU configurations
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Overview
The ASUS WS X299 Pro DDR4 is a full ATX workstation motherboard built around Intel's LGA2066 socket and the Intel X299 chipset, designed to harness the full capability of Intel Core X-Series processors. Whether you are running compute-intensive rendering workloads, multi-threaded content creation, or professional scientific applications, this board provides a stable and scalable foundation. Memory capacity scales with your processor: six-core and above Core X-Series CPUs unlock all eight DIMM slots for up to 128GB of DDR4 non-ECC unbuffered memory, while quad-core configurations support four slots and up to 64GB. In both cases, DDR4 speeds reach 4133MHz in overclocked mode, with native support at 2666, 2400, and 2133MHz. Intel Extreme Memory Profile (XMP) is supported for straightforward one-click speed enabling. Storage is generous and modern. Two M.2 Socket 3 slots operate at PCIe 3.0 x4 speeds (up to 32Gbps each), both protected beneath a dedicated M.2 heatsink that is stated to reduce drive temperatures by up to 20°C under load. Six SATA 6Gb/s ports and a single U.2 connector round out the storage options, with RAID 0, 1, 5, and 10 support via Intel Rapid Storage Technology. Intel Optane Memory compatibility is also present. Expansion slot configuration depends on the CPU's PCIe lane count: a 44-lane processor enables two full x16 slots alongside additional x8 and x4 slots, supporting NVIDIA 3-Way SLI and AMD 3-Way CrossFireX multi-GPU configurations. Connectivity at the rear I/O includes dual Intel I210-AT Gigabit LAN controllers, two USB 3.1 Gen 2 ports (one Type-A, one Type-C) via ASMedia controller, four USB 3.1 Gen 1 ports, four USB 2.0 ports, optical S/PDIF output, and 8-channel audio via a Realtek ALC S1220A codec with 120dB SNR stereo playback output. A USB BIOS Flashback button allows BIOS updates without a CPU or memory installed. Power delivery relies on a digital 8-phase CPU power design with an efficient VRM heatsink incorporating a metal fin array and connecting heatpipe. The ASUS 5-Way Optimization utility consolidates overclocking, EPU energy management, DIGI+ VRM control, Fan Xpert 4 cooling profiles, and Turbo App tuning into a single automated workflow. ASUS PRO Clock II technology provides a dedicated base-clock generator to extend overclocking margins. AURA RGB and addressable RGB headers are present for lighting customization. Verified Specifications: - Socket: Intel LGA2066 (Socket 2066) - Chipset: Intel X299 - Form Factor: ATX, 12 x 9.6 inches (30.5 x 24.4 cm) - Memory: Up to 128GB DDR4 (8 DIMM, 6-core+ CPU) / 64GB (4 DIMM, 4-core CPU); DDR4-4133(OC) to 2133MHz; XMP supported - Storage: 2x M.2 PCIe 3.0 x4 with heatsink, 1x U.2, 6x SATA 6Gb/s; RAID 0/1/5/10 - PCIe: Up to 2x PCIe 3.0 x16 (x16 mode) with 44-lane CPU; 3-Way SLI & 3-Way CrossFireX - LAN: 2x Intel I210-AT Gigabit Ethernet - Audio: Realtek ALC S1220A 7.1-channel HD audio; 120dB SNR; DTS Connect; DTS Headphone:X - USB: 2x USB 3.1 Gen 2 (Type-A + Type-C), 6x USB 3.1 Gen 1, 6x USB 2.0 - Warranty: 3 Years
Datasheet
| Warranty | 3 Years |
|---|---|
| Form Factor | ATX |
| Chipset | Intel® X299 |
| CPU Type | Intel® Socket 2066 CoreTM X-Series Processors |
| Lan | Intel® I210-AT, 2 x Gigabit LAN Controller(s) |
| Audio | Realtek® ALC S1220A 7.1-Channel High Definition Audio CODEC featuring Crystal Sound 3- Impedance sense for front and rear headphone outputs- Internal audio Amplifier to enhance the highest quality sound for headphone and speakers- Supports : Jack-detection, Multi-streaming, Front Panel MIC Jack-retasking- High quality 120 dB SNR stereo playback output (Line-out at rear) and 113 dB (Line-in)Audio Feature :- DTS Connect- DTS Headphone:X- Audio amplifier: Provides the highest-quality sound for headphone and speakers- Premium Japanese audio capacitors: Provide warm, natural and immersive sound with exceptional clarity and fidelity- Unique de-pop circuit: Reduces start-up popping noise to audio outputsSeparate layer for left and right track, ensuring both sound deliver equal qualityPremium Japan-made audio capacitors provides warm, natural, and immersive sound with exceptional clarity and fidelity |
| Memory | Intel® Core™ X-series Processors (6-core above)8 x DIMM, Max. 128GB, DDR4 4133(O.C.)/3600(O.C.)/2666/2400/2133 MHz Non-ECC, Un-buffered MemoryIntel® Core™ X-series Processors (4-core)4 x DIMM, Max. 64GB, DDR4 4133(O.C.)/3600(O.C.)/2666/2400/2133 MHz Non-ECC, Un-buffered MemorySupports Intel® Extreme Memory Profile (XMP)* Hyper DIMM support is subject to the physical characteristics of individual CPUs.* Actual memory frequency differs from Intel CPU types and memory module. Please check Intel official site for more detail about the memory types supported by each CPU |
| Storage | Intel® X299 Chipset:1 x M.2 Socket 3, with M key, type 2242/2260/2280/22110 storage devices support (PCIE 3.0 x 4 mode) *11 x M.2 Socket 3, with M key, type 2242/2260/2280 storage devices support (SATA & PCIE 3.0 x 4 mode) *21 x U.2 connector6 x SATA 6Gb/s port(s)Support Raid 0, 1, 5, 10Intel® Rapid Storage Technology 15 supportSupport Intel® Rapid Storage Technology enterprise 5.1 for X-Series (6-core and above) CPU RAIDSupports Intel® Smart Response TechnologyIntel® Optane™ Memory Ready |
| USB Ports | Intel® X299 Chipset:6 x USB 3.1 Gen 1 port(s) (4 at back panel,, 2 at mid-board)Intel® X299 Chipset:6 x USB 2.0 port(s) (4 at back panel,, 2 at mid-board)ASMedia® USB 3.1 Gen 2 controller:2 x USB 3.1 Gen 2 port(s) (2 at back panel,, Type-A + USB Type-CTM)ASMedia® USB 3.1 Gen 2 controller:1 x USB port(s) |
| Back I/O Ports | 2 x LAN (RJ45) port(s)2 x USB 3.1 Gen 2 (teal blue) Type-A + USB Type-CTM4 x USB 3.1 Gen 14 x USB 2.01 x Optical S/PDIF out1 x USB BIOS Flashback Button(s)1 x 8-channel Audio I/O |
| Expansion Slots | 44-Lane CPU-2 x PCIe 3.0 x16 (x16 mode)1 x PCIe 3.0 x16 (x8 mode)1 x PCIe 3.0 x16 (x4 mode)1 x PCIe 3.0 x4 (x4 mode)28-Lane CPU-1 x PCIe 3.0 x16 (x16 mode)1 x PCIe 3.0 x16 (x8 mode)1 x PCIe 3.0 x16 (x4 mode)1 x PCIe 3.0 x4 (x4 mode)16-Lane CPU-1 x PCIe 3.0 x16 (x8 mode)2 x PCIe 3.0 x16 (x4 mode)1 x PCIe 3.0 x4 (x4 mode) |
| Special Features | OC Design – ASUS PRO Clock II Technology5-Way Optimization by Dual Intelligent Processors 5- 5-Way Optimization tuning key perfectly consolidates TPU, EPU, DIGI+ VRM, Fan Expert 4, and Turbo AppTPUFan Xpert4- Fan Xpert 4 featuring Fan Auto Tuning function and multiple thermistors selection for optimized system cooling controlASUS 5X Protection III :- ASUS SafeSlot Core: Fortified PCIe Slot prevents damage- ASUS Overvoltage Protection: World-class circuit-protecting power design- ASUS Stainless-Steel Back I/O: 3X corrosion-resistance for greater durability!- ASUS Enhanced DRAM Overcurrent Protection – Short circuit damage prevention- ASUS ESD Guards – Enhanced ESD protectionASUS EPU:- EPUASUS Digital Power Design:- Industry Leading Digital 8 Phase CPU Power Design- Industry Leading Digital 2 Phase DRAM Power DesignAURA:- Aura RGB Strip Headers- Aura Addressable Strip Header(s)ASUS Exclusive Features:- AI Suite 3- Ai Charger+- Turbo LAN- Crystal Sound 3ASUS EZ DIY:- ASUS CrashFree BIOS- ASUS EZ Flash- ASUS USB BIOS Flashback- Multi-language BIOSASUS Q-Design:- ASUS Q-Shield- ASUS Q-Code- ASUS Q-LED (CPU, DRAM, VGA, Boot Device LED)- ASUS Q-Slot- ASUS Q-DIMM- ASUS Q-ConnectorM.2 and U.2 Onboard (The Latest Transfer Technology with up to 32Gb/s Data-transfer Speeds for M.2 and U.2)Asus Control Canter (ACC) IT management software supported |
| Multi-Gpu Support | Supports NVIDIA® 3-Way SLI™ Technology *Supports AMD 3-Way CrossFireX™ Technology * |
| Internal I/O Ports | 1 x Aura Addressable Strip Header(s)1 x AAFP connector1 x Aura RGB Strip Header1 x USB 3.1 Gen 1 connector(s) support(s) additional 2 USB 3.1 Gen 1 port(s)1 x USB 2.0 connector(s) support(s) additional 2 USB 2.0 port(s)2 x M.2 Socket 31 x TPM header6 x SATA 6Gb/s connector(s)1 x VROC_HW_Key2 x CPU Fan connector(s)1 x AIO_PUMP connector1 x Thunderbolt header(s)1 x 24-pin EATX Power connector(s)2 x 8-pin ATX 12V Power connector(s)1 x 6-pin EZ_PLUG Power connector(s)1 x EZ XMP switch1 x Front panel connector(s)1 x AUX panel header(s)1 x MemOK! button(s)1 x Thermal sensor connector(s)1 x CPU OV1 x Power-on button(s)1 x Clear CMOS button(s)1 x 5-pin EXT_FAN (Extension Fan) connector1 x Rear fan1 x COM port header1 x U.2 Connector (support U.2 NVMe device)1 x USB 3.1 Gen 2 front panel connector1 x PANEL21 x PUMP Fan connector1 x PANEL1AccessoriesUser's manual1 x Vertical M.2 bracket setI/O Shield1 x COM port cable(s)6 x SATA 6Gb/s cable(s)2 x M.2 screws1 x Supporting DVD1 x 3-Way SLI bridge(s)1 x SLI bridge(s)1 x Q-Connector1 x 2-port USB module(s)1 x Extension Cable for RGB strips (80 cm) |




