ASUS WS C621E Sage Workstation DDR4 Intel Motherboard
MPN ASUS-WS-C621E-SAGE · Brand ASUS · EEB Form Factor 12 inch x 13 inch ( 30.5 cm x 33 cm)
The ASUS WS C621E SAGE is a dual-socket Intel C621 EEB workstation motherboard with LGA 3647 support for Xeon Scalable processors, 12 DDR4 ECC DIMM slots (up to 1,536 GB), and 4-way GPU multi-graphics capability
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Overview
The ASUS WS C621E SAGE is a professional dual-socket EEB workstation motherboard designed for compute-intensive workflows including 3D rendering, video production, mechanical simulation, and multi-threaded scientific computing. Built on the Intel C621 chipset, it accommodates two Intel Xeon Scalable Processors (1st and 2nd Generation) in LGA 3647 (Socket P) sockets, each rated up to 205 W TDP, enabling symmetric multiprocessing across both CPU dies. The board's twelve DIMM slots support DDR4 RDIMM and LR-DIMM ECC memory at speeds of 2933, 2666, or 2400 MHz, with a combined maximum capacity of 1,536 GB — a critical capability for large dataset manipulation and memory-bound workloads. Error-correcting code (ECC) memory support helps maintain data integrity when running multiple RAM-intensive applications simultaneously. Graphics scalability is a standout feature: the board offers seven PCIe 3.0 x16 physical slots (three running at full x16 mode, two switchable between x16 and x8/x8, and two at x8 mode), enabling up to 4-way NVIDIA GeForce SLI, 4-way AMD CrossFireX, or 2-way NVIDIA Quadro SLI configurations. This makes the WS C621E SAGE a compelling platform for GPU-accelerated rendering and compute tasks. High-speed storage is handled by ten SATA 6 Gb/s ports (eight via the Intel C621 chipset with RAID 0/1/5/10 support, plus two from an ASMedia controller), four onboard U.2 connectors for 2.5-inch NVMe drives, and one M.2 Socket 3 (M Key) slot supporting 2242, 2260, 2280, and 22110 form factors in both SATA and PCIe modes — all capable of up to 32 Gb/s transfer rates via PCIe Gen 3.0 x4 bandwidth. NVMe PCIe SSD RAID 0 is also supported for maximum sequential throughput. Connectivity includes dual Intel I210-AT Gigabit LAN controllers, two USB 3.1 Gen 2 ports (one Type-A, one Type-C via ASMedia controller, up to 10 Gb/s), eight USB 3.1 Gen 1 ports (four back panel, four mid-board), and four USB 2.0 ports. Audio is handled by a Realtek S1220A 7.1-channel HD Audio CODEC with DTS Connect, DTS Headphone:X, optical S/PDIF output, and 32-bit/192 kHz playback support. Workstation-class reliability features include ASUS ProCool power connectors, USB BIOS Flashback for firmware recovery without a CPU or memory installed, DIGI+ VRM with a digital 7+1 phase CPU power design, SafeSlot PCIe reinforcement, TPM header, ASUS Control Center (ACC) compatibility, and an optional ASUS PIKE SAS upgrade kit. An onboard Aspeed AST2500 BMC with 64 MB VRAM provides IPMI-capable out-of-band management via an optional VGA port. Verified Specifications: - Form Factor: EEB, 12 × 13 inches (30.5 × 33 cm) - CPU Socket: Dual LGA 3647 (Socket P), Intel Xeon Scalable 1st & 2nd Gen, up to 205 W - Chipset: Intel C621 - Memory: 12 × DIMM, max 1,536 GB, DDR4 2933/2666/2400 MHz RDIMM/LR-DIMM ECC - Expansion: 7 × PCIe 3.0 x16 slots (3×x16, 2×x16/x8, 2×x8) - Storage: 10 × SATA 6Gb/s, 4 × U.2, 1 × M.2 (SATA & PCIe) - LAN: 2 × Intel I210-AT Gigabit - USB: 2 × USB 3.1 Gen 2, 8 × USB 3.1 Gen 1, 4 × USB 2.0 - Audio: Realtek S1220A 7.1-channel, 32-bit/192 kHz - Warranty: 3 Years
Datasheet
| Warranty | 3 Years |
|---|---|
| Chipset | Build in Intel® C621 |
| CPU Type | Dual Intel® Socket P (LGA 3647) for Intel® 1st and 2nd Xeon® Scalable Processors Family (205W) |
| Lan | Intel® I210-AT, 2 x Gigabit LAN Controller(s) |
| Audio | Realtek® S1220A 7.1-Channel High Definition Audio CODEC- Power pre-regulator reduces power input noise to ensure consistent performance- Impedance sense for front and rear headphone outputs- Supports : Jack-detection, Multi-streaming, Front Panel Jack-retasking- High quality SNR stereo playback output and 113 dB SNR recording input (Line-in)- Front panel audio connector (AAFP)- Supports up to 32-Bit/192kHz playbackAudio Feature :- DTS Connect- DTS Headphone:X- Optical S/PDIF out port(s) at back panel- Premium Japanese audio capacitors: Provide warm, natural and immersive sound with exceptional clarity and fidelity- Unique de-pop circuit: Reduces start-up popping noise to audio outputs |
| Memory | 12 x DIMM, Max. 1536GB, DDR4 2933/2666/2400 MHz RDIMM, LR-DIMM Memory |
| Graphic | Integrated Graphics ProcessorVGA port(Optional)- Supports VGA with max. resolution 1920 x 1200 @ 60 HzAspeed AST2500 with 64 MB VRAM |
| Storage | Intel® C621 Chipset :8 x SATA 6Gb/s port(s),Support Raid 0, 1, 5, 10ASMedia® SATA 6Gb/s controller :2 x SATA 6Gb/s port(s),4 x U.2 connector,1 x M.2 Socket 3, with M Key, type 2242/2260/2280/22110 storage devices support (both SATA & PCIE mode) |
| USB Ports | ASMedia® USB 3.1 Gen 2 controller :2 x USB port(s) (2 at back panel, , Type-A + USB Type-CTM)Intel® C621 Chipset :8 x USB 3.1 Gen 1 port(s) (4 at back panel, , 4 at mid-board)Intel® C621 Chipset :4 x USB 2.0 port(s) (2 at back panel, , 2 at mid-board) |
| Environment | Operation temperature: 10℃ ~ 35℃Non operation temperature: -40℃ ~ 70℃Non operation humidity: 20% ~ 90% ( Non condensing) |
| Back I/O Ports | 1 x PS/2 keyboard/mouse combo port(s)2 x LAN (RJ45) port(s)2 x USB 3.1 Gen 2 *44 x USB 3.1 Gen 14 x USB 2.01 x Optical S/PDIF out1 x USB BIOS Flashback® Button(s)1 x 8-channel Audio I/O |
| Expansion Slots | 3 x PCIe 3.0 x16 (x16 mode)2 x PCIe 3.0 x16 (Single at x16, dual at x8/x8)2 x PCIe 3.0 x16 (x8 mode) |
| Special Features | Gamer´s Guardian:- DIGI+ VRM- SafeSlotASUS Digital Power Design :- Industry leading Digital 7 + 1 Phase CPU Power Design- Industry leading Digital 2 Phase DRAM Power DesignASUS Exclusive Features :- Front Panel USB 3.0 SupportASUS Q-Design :- ASUS Q-Shield- ASUS Q-Code- ASUS Q-DIMMM.2 and U.2 Onboard (The Latest Transfer Technology with up to 32Gb/s Data-transfer Speeds for M.2 and U.2) |
| Multi-Gpu Support | Supports NVIDIA® 4-Way SLI™ TechnologySupports AMD 4-Way CrossFireX Technology |
| Internal I/O Ports | 2 x USB 3.1 Gen 1(up to 5Gbps) connector(s) support(s) additional 4 USB 3.1 Gen 1 port(s) 1 x USB 2.0 connector(s) support(s) additional 2 USB 2.0 port(s)1 x M.2 Socket 3 1 x TPM header1 x COM port(s) connector(s)10 x SATA 6Gb/s connector(s)1 x VROC_HW_Key2 x CPU Fan connector(s) (2 x 4 -pin)7 x Chassis Fan connector(s)2 x 8-pin EATX 12 V Power connector1 x 24-pin EATX Power connector(s)1 x VGA connector(s)1 x Front panel audio connector(s) (AAFP)1 x AUX panel header(s)1 x SMBus header(s)1 x 6-pin EATX 12V_3 Power connector1 x System panel connector4 x U.2 Connector (support U.2 NVMe device) |
| Workstation Feature | ProCool Power ConnectorUSB BIOS Flashback®ASUS PIKE SAS upgrade kit |
| Form Factor | EEB Form Factor 12 inch x 13 inch ( 30.5 cm x 33 cm) |




