MSI X299 Pro 10G DDR4 Intel Motherboard
MPN MSI-X299-PRO-10G · Brand MSI
MSI X299 Pro 10G DDR4 ATX motherboard for Intel LGA2066 X-series processors, featuring triple LAN (10GbE + 2.5GbE + 1GbE), 8 DDR4 slots up to 256GB, USB 3.2 Gen2x2 20Gbps, and dual M.2 slots on the Intel X299 chipset
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Overview
The MSI X299 Pro 10G DDR4 is a full-size ATX motherboard built on the Intel X299 chipset, designed to support Intel Core X-series processors from the 78xx, 9000, and 10000 series in the LGA2066 socket. It delivers a high-bandwidth platform for content creators, workstation users, and enthusiasts who require multi-core CPU performance alongside fast storage, networking, and connectivity. One of the most distinctive features of this board is its triple-LAN configuration. Onboard you get a 1 Gigabit Intel I219-V controller, a Realtek RTL8125-CG 2.5 Gigabit controller, and an Aquantia AQC107 10-Gigabit LAN card — giving you flexibility from basic home networking up to 10GbE infrastructure without a separate PCIe add-in card. For memory, the board offers eight DDR4 DIMM slots arranged in a quad-channel architecture, supporting up to 256GB of non-ECC unbuffered RAM. Speeds range from 2133MHz at native JEDEC up to 4200MHz under XMP overclocking profiles, with full Intel Extreme Memory Profile (XMP) support. Storage connectivity is comprehensive: two M.2 Key-M slots support PCIe 3.0 x4 and SATA 6Gb/s devices in form factors up to 22110, while six SATA 6Gb/s ports round out mass storage. RAID 0, 1, 5, and 10 are supported for SATA drives, and RAID 0 and 1 for M.2 PCIe devices. Intel Optane Memory is also supported on M2_2 when switched to PCH lanes. Expansion is handled by four PCIe 3.0 x16 slots, with lane configurations varying by CPU (up to x16/x8/x16/x8 on a 48-lane processor). Three-way NVIDIA SLI and AMD CrossFire are both supported. USB connectivity includes a rear-panel USB 3.2 Gen2x2 Type-C port delivering 20Gbps via the ASMedia ASM3242 controller, plus eight USB 3.2 Gen1 and eight USB 2.0 ports distributed across the back panel and internal headers. Audio is handled by a Realtek ALC1220 codec offering 7.1-channel high-definition audio with optical S/PDIF output. Thermal management is supported by a 4-pin CPU fan header, a dedicated water pump header, four system fan headers, and an extended PWM heatsink design. Power delivery uses dual 8-pin ATX 12V CPU connectors alongside the standard 24-pin ATX connector. A Thunderbolt add-on card connector and TPM module header are also present. Verified Specifications: - Chipset: Intel X299 - Socket: LGA2066 - CPU Support: Intel Core X-series 78xx (and above), 9000, 10000 series - Memory: 8x DDR4 DIMM, quad-channel, up to 256GB, 2133–4200(OC) MHz, XMP support - Storage: 6x SATA 6Gb/s, 2x M.2 (PCIe 3.0 x4 / SATA, up to 22110) - Expansion: 4x PCIe 3.0 x16 slots; 3-Way SLI / CrossFire - LAN: Intel I219-V (1GbE) + Realtek RTL8125-CG (2.5GbE) + Aquantia AQC107 (10GbE) - USB: 1x USB 3.2 Gen2x2 20Gbps Type-C (rear), 1x USB 3.2 Gen2 10Gbps Type-C (internal), 8x USB 3.2 Gen1, 8x USB 2.0 - Audio: Realtek ALC1220, 7.1-channel HD Audio, S/PDIF optical out - Form Factor: ATX, 12 in. x 9.6 in. (30.5 cm x 24.4 cm) - OS Support: Windows 10 64-bit - Warranty: 3 Years
Datasheet
| Warranty | 3 Years |
|---|---|
| Chipset | Intel® X299 Chipset |
| Lan | 1 x Intel I219-V Gigabit LAN controller1 x Realtek RTL8125-CG 2.5G LAN controller1 x Aquantia® AQC107 10-Gigabit LAN cardI219 LAN doesn’t support G3 to S5 Wake |
| USB | ASMedia® ASM3242 Chipset1 x USB 3.2 Gen2x2 (SuperSpeed USB 20Gbps) Type-C port on the back panelASMedia® ASM3142 Chipset1 x USB 3.2 Gen2 (SuperSpeed USB 10Gbps) Type-C internal connectorIntel® X299 Chipset8 x USB 3.2 Gen1 (SuperSpeed USB) ports (4 ports on the back panel, 4 ports available through the internal USB connectors)8 x USB 2.0 (High-speed USB) ports (4 ports on the back panel, 4 ports available through the internal USB connectors) |
| Raid | Intel® X299 ChipsetSupports RAID 0, RAID1, RAID 5 and RAID 10 for SATA storage devicesSupports RAID 0 and RAID 1 for M.2 PCIe storage devices |
| Audio | Realtek® ALC1220 Codec7.1-Channel High Definition AudioSupports S/PDIF output |
| Slots | 4x PCIe 3.0 x16 slots Support x16/x8/x16/x8 mode with the 48-lane CPU.Support x16/x4/x16/x8 mode with the 44-lane CPU.Support x16/x4/x8/x0 mode with the 28-lane CPU.Please refer to user manual for PCIe 3.0 bandwidth table |
| Memory | 8 x DDR4 memory slots, support up to 256GBSupports DDR4 4200 (OC)/ 4000(OC)/ 3800 (OC)/ 3733(OC)/ 3600(OC)/ 3466(OC)/ 3400(OC)/ 3333(OC)/ 3300(OC)/ 3200(OC)/ 3000(OC)/ 2933/ 2666/ 2400/ 2133 MHz Quad channel memory architectureSupports Intel® Extreme Memory Profile (XMP)Supports non-ECC UDIMM memorySupports un-buffered memory |
| Storage | Intel® X299 Chipset6 x SATA 6Gb/s ports2 x M.2 slot (Key M)Support up to PCIe 3.0 x4 and SATA 6Gb/s, 2242/ 2260/ 2280/ 22110 storage devicesIntel® Optane™ Memory ReadyThe SATA1 connector will be unavailable when a SATA M.2 SSD has been installed in the M2_1 slot.The M2_2 default setting is CPU lane. However, when a PCIe expansion card is installed in the PCI_E2 slot, the M2_2 will be automatically switched to PCH lane.The SATA2 connector will be unavailable when M2_2 uses PCH lanes and a M.2 SATA SSD is installed in the M2_2 slot.M2_2 supports Intel® Optane™ Memory by switching to PCH lanes |
| Mounting | 9 mounting holes |
| Multi-Gpu | Supports 3-Way NVIDIA® SLI™ TechnologySupports 3-Way AMD® CrossFire™ Technology |
| Processor | Supports Intel® Core™ X-series 10000/ 9000/ 78xx (above) processors for socket LGA2066 |
| Dimensions | 12 in. x 9.6 in. (30.5 cm x 24.4 cm)ATX Form Factor |
| Back Panel Ports | Keyboard / MouseGigabit LAN2.5G LANAudio ConnectorsUSB 2.0Clear CMOS ButtonUSB 2.0USB 3.2 Gen1 Type-AUSB 3.2 Gen1 Type-AUSB 3.2 Gen2x2 20G Type-COptical S/PDIF out |
| Operating System | Support for Windows® 10 64-bit |
| Internal Connectors | 1 x 24-pin ATX main power connector2x 8-pin ATX 12V power connectors6x SATA 6Gb/s connectors2x USB 2.0 connectors (supports additional 4 USB 2.0 ports)2x USB 3.2 Gen1 connectors (supports additional 4 USB 3.2 Gen1 ports)1x USB 3.2 Gen2 Type-C port1x 4-pin CPU fan connector1x 4-pin Water Pump connector4x 4-pin system fan connectors1x Front panel audio connector2x System panel connectors1x TPM module connector1x Chassis Intrusion connector1x Virtual RAID on CPU connector1x Thunderbolt Add-on Card Connector |




