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Motherboards

MSI Pro B850-S Wifi6e DDR5 AMD Motherboard

MPN MSI-PRO-B850-S-WIFI6E-DDR5  ·  Brand MSI

The MSI PRO B850-S WiFi 6E is an ATX motherboard with AMD B850 chipset, AM5 socket, PCIe 5.0 M.2 storage, DDR5 support up to 8200+ MT/s, Wi-Fi 6E, and 2.5G LAN — built for Ryzen 9000/8000/7000 series processors

Chipset AMD B850 Lan Realtek® 8125 2.5G LAN Model PRO B850-S WIFI6E Pcb Info ATX243.84mmx304.8mm
16,250.00

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01

Overview

The MSI PRO B850-S WiFi 6E is an ATX form-factor motherboard built on the AMD B850 chipset, designed for professionals and productivity-focused builders who want a clean, future-ready platform without unnecessary extras. Its understated black aesthetic integrates seamlessly into dark PC builds, while the engineering beneath the surface is built for demanding workloads. At the core of the connectivity stack is Wi-Fi 6E (802.11ax) with support for 2.4 GHz, 5 GHz, and 6 GHz bands at up to 2.4 Gbps over 160 MHz channels, complemented by MU-MIMO TX/RX and Bluetooth 5.3. Wired networking is handled by a Realtek RTL8125 2.5G LAN controller, providing low-latency, high-throughput connectivity for demanding data transfers and online workloads. The board accommodates AMD Ryzen 9000, 8000, and 7000 series processors via the AM5 socket and includes dual CPU power connectors alongside a 12+2+1 digital power phase design to support sustained high-performance operation. Memory is handled by four DDR5 UDIMM slots supporting up to 256 GB, with JEDEC speeds from 4800 to 5600 MT/s and overclocked profiles reaching up to 8200+ MT/s (1DPC 1R) via AMD EXPO and manual XMP-style tuning. Dual-channel operation is supported. Storage options include two M.2 slots — the primary M.2_1 (from CPU) supports PCIe 5.0 x4 for Ryzen 9000/7000 processors and is covered by MSI's M.2 Shield Frozr heatsink, while M.2_2 supports PCIe 4.0 x4. Four SATA 6 Gbps ports round out storage connectivity. RAID configurations include RAID 0, 1, and 10 for SATA, and RAID 0 and 1 for NVMe. Expansion slots include two PCIe x16 physical slots and one PCIe x1 slot: PCI_E1 runs at PCIe 4.0 x16 (for Ryzen 9000/7000) from the CPU, while PCI_E3 runs at PCIe 4.0 x4 from the chipset. USB connectivity is comprehensive, with 10 Gbps Type-A and Type-C ports on both the rear panel and front-panel headers. Onboard display outputs include HDMI 2.1 and DisplayPort 1.4, both capable of up to 4K 60 Hz when using a processor with integrated graphics. Audio is driven by a Realtek ALC897 codec delivering 7.1-channel HD audio. Internal RGB is supported through three ARGB V2 headers and one standard RGB header. EZ Debug LEDs and an EZ Memory Detection LED aid rapid troubleshooting. The board also includes a Flash BIOS button and Clear CMOS button on the rear I/O panel, plus a TPM 2.0 header. Verified Specifications: - Form Factor: ATX (243.84 mm x 304.8 mm) - Chipset: AMD B850 - Socket: AM5 (Ryzen 9000 / 8000 / 7000 series) - Memory: 4x DDR5 UDIMM, max 256 GB; up to 8200+ MT/s (OC, 1DPC 1R) - M.2 Slots: 2x (PCIe 5.0 x4 + PCIe 4.0 x4) - SATA: 4x 6 Gbps - PCIe: x16 (PCIe 4.0, CPU), x1 (PCIe 3.0, Chipset), x4 (PCIe 4.0, Chipset) - LAN: Realtek 8125, 2.5 Gbps - Wireless: Wi-Fi 6E (160 MHz, up to 2.4 Gbps), Bluetooth 5.3 - Audio: Realtek ALC897, 7.1-channel HD - Rear USB: 3x USB 10 Gbps Type-A, 1x USB 10 Gbps Type-C, 4x USB 5 Gbps Type-A - Video Out: HDMI 2.1 (4K 60Hz), DisplayPort 1.4 (4K 60Hz) - Power Design: 12+2+1 digital power phases

02

Datasheet

Chipset

AMD B850

CPU Type

Supports AMD RyzenTM 9000/ 8000/ 7000 Series Desktop ProcessorsSocket AM5

Lan

Realtek® 8125 2.5G LAN

USB

4x USB 2.0 (Front)4x USB 5Gbps Type A (Rear)2x USB 5Gbps Type A (Front)3x USB 10Gbps Type A (Rear)1x USB 10Gbps Type C (Rear)1x USB 10Gbps Type C (Front)

Raid

Supports RAID 0, RAID 1, and RAID 10 for SATA storage devicesSupports RAID 0 and RAID 1 for M.2 NVMe storage devices

Slot

2x PCI-E x16 slot1x PCI-E x1 slotPCI_E1 Gen PCIe 4.0 supports up to x16 (From CPU) PCI_E2 Gen PCIe 3.0 supports up to x1 (From Chipset) PCI_E3 Gen PCIe 4.0 supports up to x4 (From Chipset) PCI_E1 slot• Supports PCIe 4.0 x16 (For Ryzen™ 9000/ 7000 Series processors)• Supports PCIe 4.0 x8 (For Ryzen™ 8700/ 8600/ 8400 Series processors)• Supports PCIe 4.0 x4 (For Ryzen™ 8500/ 8300 Series processor)

Audio

Realtek® ALC8977.1-Channel High Definition Audio

Model

PRO B850-S WIFI6E

Memory

4x DDR5 UDIMM, Maximum Memory Capacity 256GBMemory Support DDR5 8200 – 5600 (OC) MT/s / 5600 – 4800 (JEDEC) MT/sRyzen™ 9000 Series Processors max. overclocking frequency:• 1DPC 1R Max speed up to 8200+ MT/s• 1DPC 2R Max speed up to 6400+ MT/s• 2DPC 1R Max speed up to 6400+ MT/s• 2DPC 2R Max speed up to 6000+ MT/sSupports AMD POR Speed and JEDEC SpeedSupports Memory Overclocking and AMD EXPOTMSupports Dual-Channel modeSupports Non-ECC, Un-buffered memorySupports CUDIMM, Clock Driver bypass mode only** CUDIMM support and POR boot frequency may vary by CPU series, with manual overclocking available after boot. Certain CPUs may fail to boot, but future BIOS updates will improve compatibility.• The DIMM slots on this motherboard only have single-sided latches.• Memory compatibility and supported speeds can vary depending on the CPU and memory configuration. For detailed information, please refer to the Memory Compatibility List available on the product’s Support page or visit https://www.msi.com/support/

Storage

2x M.2M.2_1 Source (From CPU) supports up to PCIe 5.0 x4 , supports 22110/2280 devices M.2_2 Source (From CPU) supports up to PCIe 4.0 x4 , supports 2280/2260 devices 4x SATA 6GM2_1 slot• Supports up to PCIe 5.0 x4 (For Ryzen™ 9000/ 7000 Series processors)• Supports up to PCIe 4.0 x4 (For Ryzen™ 8000 Series processors)M2_2 slot• Supports up to PCIe 4.0 x4 (For Ryzen™ 9000/ 8700/ 8600/ 8400/ 7000 Series processors)• Supports up to PCIe 4.0 x2 (For Ryzen™ 8500/ 8300 Series processors)*Please refer to the manual for M.2 SSD heatsink restrictions

Pcb Info

ATX243.84mmx304.8mm

Internal Io

1x Power Connector(ATX_PWR)2x Power Connector(CPU_PWR)1x CPU Fan1x Combo Fan (Pump_Sys Fan)4x System Fan2x Front Panel (JFP)1x Chassis Intrusion (JCI)1x Front Audio (JAUD)1x Com Port (JCOM)1x Tuning Controller connector(JDASH)3x Addressable V2 RGB LED connector (JARGB_V2)1x RGB LED connector(JRGB)1x TPM pin header(Support TPM 2.0)4x USB 2.0 ports2x USB 5Gbps Type A ports1x USB 10Gbps Type C ports

Led Feature

4x EZ Debug LED1x EZ Memory Detection LED

Back Panel Ports

Clear CMOS ButtonDisplayPort2.5G LANUSB 10Gbps Type-AUSB 5Gbps Type-AWi-Fi / BluetoothAudio ConnectorsFlash BIOS ButtonHDMI™USB 10Gbps Type-AUSB 10Gbps Type-C

Onboard Graphics

1x HDMI™Support HDMITM 2.1, maximum resolution of 4K 60Hz*1x DisplayPortSupport DisplayPort 1.4, maximum resolution of 4K 60Hz**Available only on processors featuring integrated graphics. Graphics specifications may vary depending on the CPU installed

Wireless Lan & Bluetooth

Wi-Fi 6EThe Wireless module is pre-installed in the M.2 (Key-E) slotSupports MU-MIMO TX/RX, 2.4GHz/ 5GHz/ 6GHz* (160MHz) up to 2.4GbpsSupports 802.11 a/ b/ g/ n/ ac/ axSupports Bluetooth® 5.3**, FIPS, FISMA* 6GHz band support may depend on every country’s regulations and Wi-Fi 6E requires Windows 11.** The Bluetooth version may be updated, please refer to the Wi-Fi chipset vendor’s website for details

03

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